Topiramate-induced reversible auditory hallucination.

Topiramate (TPM) is an antiepileptic drug also used in migraine prophylaxis (Silberstein et al. 2007). Neuropsychiatric symptoms may emerge during the use of TPM (Fröscher et al. 2005). There are few reports showing a link between psychotic adverse events and use of TPM (Khan et al. 1999). Only one patient with schizoaffective disorder has been reported in the litera ture, who complained of dose-related, auditory hallucinations with TPM use (Matthews and Miller 2001). We report a patient with migraine who presented with reversible, dose-related, auditory hallucinations during TPM treatment.